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Bioprocess Development

CUSTOMIZED FUNCTIONAL PROTEIN PRODUCTION

EUCODIS Bioscience provides one-to-one support during every step of product development – from discovery stage to product candidate selection to final product formulation.

EUCODIS Bioscience has extensive experience and capabilities to express and purify proteins in quantities ranging from milligrams up to kilogram scale. We are specialists in setting up new bioprocesses for the scale-up and manufacture of the desired product according to our customers’ requirements. Stringent process controls under ISO 9001 are in place to ensure that recombinant proteins and enzymes are manufactured in reproducible manner and in highest quality.

We use a variety of expression systems:
Bacteria (E. coli, B. subtilis)
Yeasts (P. pastoris, S. cerevisiae)
Fungi (A. oryzae)

Our services include:

  • Cloning and expression
  • Selection of optimal expression system and conditions
  • Fermentation optimization to increase protein yields and stability
  • High content multiwell screening
  • Multi-parallel 1 L fermentations (DASGIP)
  • 1 L – 10 L Infors/Labfors
  • Professional upscale in 1 L to 1000 L bioreactors - depending on customer demand
    (1 L, 10 L, 20 L,50 L, 200 L and 1000 L)